RNAs: regulators of bacterial virulence
نویسندگان
چکیده
منابع مشابه
Selection for in vivo regulators of bacterial virulence.
We devised a noninvasive genetic selection strategy to identify positive regulators of bacterial virulence genes during actual infection of an intact animal host. This strategy combines random mutagenesis with a switch-like reporter of transcription that confers antibiotic resistance in the off state and sensitivity in the on state. Application of this technology to the human intestinal pathoge...
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Circular RNAs (circRNAs) are highly stable, circularized long non-coding RNAs. circRNAs are conserved across species and appear to be specifically enriched in the nervous system. Recent studies show that many circRNAs are expressed in a tissue- and developmental-stage-specific manner, reveal a striking regulation of circRNAs during neuronal development, and detect their presence at synaptic sit...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2010
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro2457